SAM Complex: A Drug Target for Cellular Processes (P18411)

Target Name: Sorting and assembly machinery complex

NCBI ID: P18411

Sorting and assembly machinery complex

Other Name(s): SAM complex

SAM Complex: A Drug Target for Cellular Processes

Sorting and assembly machinery complex (SAM complex) is a protein that plays a crucial role in many biological processes, including cell division, development, and tissue repair. The SAM complex is made up of a complex network of proteins that work together to ensure the accurate and efficient sorting of chromosomes during cell division. Sorting and assembly machinery complex is a drug target (or biomarker) that may be targeted by researchers to study a variety of cellular processes, including cancer, neurodegenerative diseases, and genetic disorders.

The SAM complex is composed of several key proteins, including:

1. coiled coiled protein 2 (C2): C2 is the protein that forms the core of the SAM complex and is responsible for organizing and coordinating the assembly of the other proteins in the complex.
2. protein 3 (P1): P1 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
3. protein 4 (P2): P2 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
4. protein 5 (P3): P3 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
5. protein 6 (P4): P4 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
6. protein 7 (P5): P5 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
7. protein 8 (P6): P6 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
8. protein 9 (P7): P7 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.
9. protein 10 (P8): P8 is a protein that interacts with C2 and is involved in the assembly and disassembly of the SAM complex.

The SAM complex plays a central role in ensuring the accurate and efficient sorting of chromosomes during cell division. During cell division, the SAM complex helps to identify the chromosomes that contain genetic information and direct them to the correct position during cell division. This ensures that Each new cell receives an accurate copy of the genetic information from its parent cell.

The SAM complex is also involved in the assembly and disassembly of other proteins, including the telomere and the microtubules. Tubulin is a protein that forms the spindle in the nucleus. Important ingredient that helps chromosomes segregate correctly into two new cells during cell division.

In some diseases, such as cancer, neurodegenerative diseases, and genetic disorders, dysregulation of the SAM complex may lead to abnormal chromosome segregation, leading to cell division and incorrect transmission of genetic information. Therefore, studying the biological functions of SAM complex is of great significance for understanding the pathogenesis of these diseases and developing new treatment strategies.

In recent years, researchers have discovered some interactions and regulatory mechanisms of the SAM complex. For example, studies have found that P1 and P2 are two important components in the SAM complex. They can interact and participate in the assembly and disassembly of the SAM complex. In addition, the researchers also found that P3 and P4 also play an important role in the SAM complex, and they may be involved in the assembly and disassembly process of the SAM complex.

In addition, some studies have also shown that the imbalance of SAM complex is related to the occurrence and development of some diseases. For example, studies have found that dysregulation of the SAM complex is associated with neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. In addition, some studies have also shown that the dysregulation of SAM complex is related to the onset and development of cancer.

Therefore, the SAM complex is an interesting drug target (or biomarker)

Protein Name: Sorting And Assembly Machinery Complex

The "Sorting and assembly machinery complex Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Sorting and assembly machinery complex comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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